Nakayama, T. and Ishii, T.:
Molecular interaction of tea catechins with phospholipids-roles on their biological activities and tastes, The 1st International Conference on Pharma-Food (Shizuoka,Japan),2012年11月15日
Mayumi Takada, Kazuki Kimura, Takeshi Ishii, Kentaro Naito, and Mitsugu Akagawa:
Pyrroloquinoline quinone (PQQ) activates insulin signaling in mouse C2C12 myotubes by inhibiting protein tyrosine phosphatase 1B.
2011 International Conference of Food Factors (Taipei, Taiwan), 2011年11月21日
Mitsugu Akagawa, Tomoko Tanaka, Daisuke Mizuno, Taiki Mori, Ryoichi Yamaji, Yoshimasa Nakamura, Shigenori Kumazawa, Tsutomu Nakayama, and Takeshi Ishii:
(-)-Epigallocatechin-3-gallate suppresses growth of AZ521 human gastric cancer cells by targeting the DEAD box RNA helicase p68.
2011 International Conference of Food Factors (Taipei, Taiwan), 2011年11月21日
Hiromi Uezono, Takeshi Ishii, and Tsutomu Nakayama:
Astringency of theaflavins, red pigments in black tea.
第16回健康・長寿学術フォーラム(静岡), 2011年10月21日
Yoshinori Uekusa, Miya Kamihira-Ishijima, Osamu Sugimoto, Ken-ichi Tanji, Kozo Nakamura, Takeshi Ishii, Shigenori Kumazawa, Akira Naito, Tsutomu Nakayama, Koichi Kato:
The molecular mechanism of the interaction between tea catechins and phospholipid membranes by NMR spectroscopy.
The Winter School of SOKENDAI/Asian Core Program Frontiers of Molecular Science - Life, Material, Energy, and Space, (Okazaki, Japan), 2011年2月20日
2010年
Kohta Ohnishi, Taiki Mori, Takeshi Ishii, Tsutomu Nakayama, Akari Ishisaka, Yoshichika Kawai, Junji Terao, Noriyuki Kioka, Kazuhiro Irie, and Akira Murakami:
Zerumbone is covalently bound to the key proteins involved in inflammatory and self-defense mechanisms.
The 2010 International Chemical Congress of Pacific Basin Societies (Hawaii, USA), 2010年12月18日
Tatsuya Ichikawa, Takeshi Ishii, Kanako Minoda, Min-Jung Bae, and Tsutomu Nakayama:
Human serum albumin as an antioxidant for oxidation of (-)-epigallocatechin gallate.
The 2010 International Chemical Congress of Pacific Basin Societies (Hawaii, USA), 2010年12月16日
Yoshinori Uekusa, Miya Kamihira-Ishijima, Osamu Sugimoto, Takeshi Ishii, Shigenori Kumazawa, Kozo Nakamura, Ken-ichi Tanji, Koichi Kato, Akira Naito, and Tsutomu Nakayama:
Interaction of epicatechin gallate with model phospholipid membranes as revealed by solid-state NMR spectroscopy.
The 2010 International Chemical Congress of Pacific Basin Societies (Hawaii, USA), 2010年12月16日
Tomoharu Katsumata, Takeshi Ishii, and Tsutomu Nakayama:
Interaction of tea catechins with serum and cell proteins.
Biochemistry and Molecular Biology 2010 (Kobe), 2010年12月7日
Taiki Mori, Takeshi Ishii, and Tsutomu Nakayama:
Structural characteristics of tea catechins for formation of protein carbonyl in human serum albumin.
Biochemistry and Molecular Biology 2010 (Kobe), 2010年12月7日
Tatsuya Ichikawa, Takeshi Ishii, Erika Shibuya, and Tsutomu Nakayama:
Milk casein functions as an antioxidant in the oxidation of (-)-epigallocatechin gallate.
The 4th International Conference on O-CHA (Tea) Culture and Sciences (Shizuoka, Japan), 2010年10月27日
Tatsuya Ichikawa, Takeshi Ishii, Erika Shibuya, and Tsutomu Nakayama:
Inhibition of soy bean lipoxygenase by tea catechins through their covalent binding.
The 4th International Conference on O-CHA (Tea) Culture and Sciences (Shizuoka, Japan), 2010年10月27日
Tomoharu Katsumata, Takeshi Ishii, Yumi Yamada, and Tsutomu Nakayama:
Interaction of tea catechins with serum proteins:Development and application of a new probe for understanding the action of catechins.
The 4th International Conference on O-CHA (Tea) Culture and Sciences (Shizuoka, Japan), 2010年10月27日
Koji Kusaka, Takeshi Ishii, and Tsutomu Nakayama:
Structural characteristics of tea catechins that affect their binding affinity with cyclodextrins.
The 4th International Conference on O-CHA (Tea) Culture and Sciences (Shizuoka, Japan), 2010年10月27日
Koji Kusaka, Takeshi Ishii, Miu Hiramatsu, and Tsutomu Nakayama:
Stability of (-)-epigallocatechin gallate in aqueous solutions containing food constituents:Synergy of antioxidant property and binding capacity.
The 4th International Conference on O-CHA (Tea) Culture and Sciences (Shizuoka, Japan), 2010年10月27日
Takeshi Ishii, Taiki Mori, Kota Miyajima, Mitsugu Akagwa, Toshiyuki Kan, and Tsutomu Nakayama:
Formation of protein carbonyl in human serum albumin by tea catechins.
The 4th International Conference on O-CHA (Tea) Culture and Sciences (Shizuoka, Japan), 2010年10月27日
Taiki Mori, Takeshi Ishii, Mitsugu Akagawa, Yoshimasa Nakamura, and Tsutomu Nakayama:Electrophilic reactivity of tea catechins toward protein sulfhydryls.
The 4th International Conference on O-CHA (Tea) Culture and Sciences (Shizuoka, Japan), 2010年10月27日
Hiromi Uezono, Takeshi Ishii, Yoshinori Uekusa, and Tsutomu Nakayama:
Interaction of theaflavins with phospholipids and proteins.
The 4th International Conference on O-CHA (Tea) Culture and Sciences (Shizuoka, Japan), 2010年10月27日
Tomoharu Katsumata, Takeshi Ishii, and Tsutomu Nakayama:
A search for the high-affinity proteins of tea catechins in human cell lysates.
The 4th International Conference on O-CHA (Tea) Culture and Sciences (Shizuoka, Japan), 2010年10月27日
Outstanding Poster Award 受賞
Tomoko Tanaka, Takeshi Ishii, Daisuke Mizuno, Taiki Mori, Ryoichi Yamaji, Yoshimasa Nakamura, Shigenori Kumazawa, Tsutomu Nakayama, and Mitsugu Akagawa:
Epigallocatechin-3-gallate induces growth inhibition of human gastric cancer cell line AZ521 cells by targeting the DEAD box RNA helicase p68.
The 4th International Conference on O-CHA (Tea) Culture and Sciences (Shizuoka, Japan), 2010年10月27日
Yoshinori Uekusa, Miya Kamihira-Ishijima, Osamu Sugimoto, Takeshi Ishii, Shigenori Kumazawa, Kozo Nakamura, Ken-ichi Tanji, Koichi Kato, Akira Naito, and Tsutomu Nakayama:
The study of caechin-phospholipid membranes interaction by solution and solid-state NMR spectroscopy.
The 4th International Conference on O-CHA (Tea) Culture and Sciences (Shizuoka, Japan), 2010年10月27日
Yoshinori Uekusa, Miya Kamihira-Ishijima, Osamu Sugimoto, Takeshi Ishii, Shigenori Kumazawa, Kozo Nakamura, Ken-ichi Tanji, Koichi Kato, Akira Naito, and Tsutomu Nakayama:
The molecular aspects of green tea catechin interacting with phospholipid membranes as revealed by solution and solid-state NMR spectroscopy.
24th International Conference on Magnetic Resonance in Biological Systems (Cairns, Australia), 2010年8月26日
Yoshinori, Uekusa, Miya Kamihira, Osamu Sugimoto, Kenichi Tanji, Kozo Nakamura,Takeshi Ishii, Shigenori Kumazawa, Akira Naito, and Tsutomu Nakayama:
Solid-state NMR study of the interaction between epicatechin gallate and phospholipid membranes.
4th International Conference on Polyphenols and Health (Yorkshire, UK),2009年12月8日
Tsutomu Nakayama, Shigenori Kumazawa, Takeshi Ishii, and Yoshinori Uekusa
NMR study on
interaction between tea polyphenols and model lipid memblanes.
1st
International Conference on Health and Longevity Sciences (Shizuoka, Japan),
2008年12月19日
Takeshi Ishii, Sohei Ito, Taiki Mori, Shigenori Kumazawa, Tsutomu Nakayama, and Koji
Uchida
Site-specific modification of positively-charged surfaces on human
serum albumin by malondialdehyde.
Lipd Peroxidation 2008
(Karuizawa, Japan), Oct, 2008
Takeshi Ishii, Taiki Mori, Shigenori Kumazawa, Tsutomu Nakayama, and Koji Uchida
Mass spectrometric
characterization of acrolein induced protein cross-links.
Lipd
Peroxidation 2008 (Karuizawa, Japan), Oct, 2008
Yoshinori, Uekusa, Miya Kamihira, Takeshi Ishii, Shigenori Kumazawa, Tsutomu Nakayama
Dynamic behavior
of tea polyphenols (catechins) interacting with lipid membranes determined by
solution NMR spectroscopy.
The 9th International Conference on
the Applications of Magnetic Resonance in Food Science (Republic, Iceland), Sep
2008.
石野孔祐、石井剛志、柴田貴広、Liu Yu-Tang、豊國伸哉、Zhu Xiaochun、Sayre Lawrence M、内田浩二
過酸化水素を介した新しいタンパク質のアルデヒド修飾反応
第61回日本酸化ストレス学会学術集会 (京都)、2008年6月20日
Taiki Mori, Takeshi Ishii, Tomoko Tanaka, Daisuke Mizuno, Shigenori Kumazawa, Noriyuki Miyoshi,
Mitsugu Akagawa, and Tsutomu Nakayama
Regulation of thiol enzyme activity by
(-)-epigallocatechin gallate through covalent binding to cysteine.
2008ASBMB Annual
Meeting (San Diego, CA, USA) 2008年4月8日
Noriko Iwamoto, Daigo Sumi, Takeshi Ishii, Koji Uchida, Yoshito Kumagai
Arylation of protein tyrosine
phosphatase 1B by 1,2-naphthoquinone through Cys-121 causes prolonged
phosphorylation of epidermal growth factor receptor.
The 2nd JST-ERATO
Yamamoto Environmental Response Project International Symposium (Tsukuba,
Japan), Dec 2007.
Naoyuki Takayama, Noriko Iwamoto, Takeshi Ishii, Daigo Sumi, Yoshito Kumagai
Arylation of peroxiredoxin 6 by
1,2-naphthoquinone through Lys209 causes reduction of its phospholipase A2
activity.
The 2nd JST-ERATO Yamamoto Environmental Response Project
International Symposium (Tsukuba, Japan), Dec 2007.
Kousuke Ishino, Takahiro Shibata, Takeshi Ishii, Shinya Toyokuni, and Koji Uchida
Oxidative modification of protein
by lipid peroxidation products: H2O2-catalyzed protein N-acylation by saturated aldehydes.
The 4th Joint Meeting of the
Society for Free Radical Research Australia and Japan (Kyoto, Japan), Dec
2007.
Taiki Mori, Takeshi Ishii, Chikako Nakayama, Mitsugu Akagawa, and Tsutomu Nakayama
Protein oxidative modification with pyrroloquinoline
quinone.
International Conference of Food Factors for Health Promotion 2007
(Kyoto, Japan), Nov 2007.
Poster Award
受賞
Taiki Mori, Takeshi Ishii, Miyuki Wakabayashi, Mitsugu Akagawa, and Tsutomu Nakayama
Mass spectrometry-based
study of protein redox modification by alpha-lipoic acid.
International
Conference of Food Factors for Health Promotion 2007 (Kyoto, Japan), Nov
2007.
Tomoko Tanaka, Daisuke Mizuno, Takeshi Ishii, Taiki Mori, Ryoichi Yamaji, Shigenori Kumazawa, Tsutomu Nakayama, and
Mitsugu Akagawa
Proteomic identification of
epigallocatechin-3-gallate-binding protein in AZ521 human gastric cancer
cells.
3rd International Conference on Polyphenols and Health (Kyoto, Japan),
Nov 2007.
Taiki Mori, Takeshi Ishii, Tomoko Tanaka, Daisuke Mizuno, Shigenori Kumazawa, Ryoichi Yamaji, Mitsugu Akagawa, and Tsutomu Nakayama
(-)-Epigallocatechin gallate regulates thiol enzyme
activity by covalent binding to cysteine residues.
3rd International
Conference on Polyphenols and Health (Kyoto, Japan), Nov 2007.
Takeshi Ishii, Min-Jung Bae, Yukiko Kawada, and Tsutomu Nakayama
Effects of human serum albumin on stability of
(-)-epigallocatechin-gallate.
3rd International Conference on Polyphenols and
Health (Kyoto, Japan), Nov 2007.
Yoshinori Uekusa, Miya Kamihira, Takeshi Ishii, Shigenori Kumazawa, Kozo Nakamura, and Tsutomu Nakayama
Dynamic
behavior of tea polyphenols interacting with lipid bilayres as determined by NMR
spectroscopy.
3rd International Conference on Polyphenols and Health (Kyoto,
Japan), Nov 2007.
Noriko Iwamoto, Daigo Sumi, Takeshi Ishii, Koji Uchida and Yoshito Kumagai
Covalent modification of proein
tyrosine phosphatase 1B by 1,2-naphthoquinone.
SFRBM’s 14th Annual Meeting
(Washington, DC, USA), Nov 2007.
Yuko Takeshita, Yoshinori Uekusa, Takeshi Ishii, and Tsutomu Nakayama
Interaction of tea catechins with lipid
bilayers investigate by immobilized artifical membrane chromatography.
The
3rd International Conference on O-CHA (Tea) Culture and Science (Shizuoka
Japan), Nov 2007.
Best Poster Award受賞
Tomohisa Takagi, Yuji Naito, Takahiro Suzuki,
Hirokazu Kajikawa, Takeshi Ishii, Kouichi Terao, Hisato Tsuboi, Kazuhiro
Kamada, Toshimitsu Okuda, Osamu Handa, Satoshi Kokura, Hiroshi Ichikawa,
Norimasa Yoshida, and Toshikazu Yoshikawa Induction of heme oxygenase-1 by an
endogenous electrophile, 15-deoxy-Δ12,14-prostaglandin
J2, ameliorates dextran sodium sulfate-induced colitis in
mice. 13th Biennial Meeting of the Society for Free Radical Research
International (Davos, Swithzerland), August 2006.
Osamu Handa, Yuji Naito, Takeshi Ishii,
Katsura Mizushima, Tomohisa Takagi, Satoshi Kokura, Hiroshi Ichikawa, Norimasa
Yoshida, Hirofumi Matsui, Sunao Kawano, Toshikazu Yoshikawa Cytotoxin-associated gene product A (CagA) of Helicobacter
pylori increases mitochondria dependent oxidative stress in rat gastric
epithelial cell. 13th Biennial Meeting of the Society for Free Radical
Research International (Davos, Swithzerland), August 2006.
Osamu Handa, Yuji Naito, Takeshi Ishii,
Satoko Adachi, Tomohisa Takagi, Norimasa Yoshida, Toshikazu
Yoshikawa Cytotoxin-associated gene product A of Helicobacter pylori
induced cellular response in rat gastric epithelial cell. 12th International
Conference on Ulcer Research/GI Satellite of IUPHAR 2006 (Osaka, Japan), July
2006.
Takeshi Ishii, Mitsugu Akagawa, Yuji
Naito, Toshikazu Yoshikawa, and Shigenori Kumazawa Mass spectroscopic
characterization of protein oxidation by pyrroloquinoline quinone. 54th ASMS
Conference on Mass Spectrometry (Seattle, USA), June 2006.
Tomohisa Takagi, Yuji Naito, Takahiro Suzuki,
Hirokazu Kajikawa, Kouichi Terao, Hisato Tsuboi, Takeshi Ishii, Kazuhiro
Kamada, Toshimitsu Okuda, Osamu Handa, Satoshi Kokura, Hiroshi Ichikawa,
Norimasa Yoshida, and Toshikazu
Yoshikawa 15-Deoxy-delta12,14-prostaglandin J2
ameliorates dextran sodium sulfate-induced colitis in mice via induction of heme
oxygenase-1. AGA 2006 (Los Angeles, USA), May 2006.
Osamu Handa, Yuji Naito, Takeshi Ishii,
Hisato Tsuboi, Satoko Adachi, Tomohisa Takagi, Satoshi Kokura, Norimasa Yoshida,
Hirofumi Matsui,Takeshi Azuma, Hai Ying Fu, Sunao Kawano, Toshikazu
Yoshikawa Helicobacter pylori Cag A induces mitochondria-dependent
production of reactive oxygen species in gastric epithelial cell. AGA 2006
(Los Angeles, USA), May 2006.
Tomohisa Takagi, Yuji Naito, Takahiro Suzuki,
Kouichi Terao, Hirokazu Kajikawa, Hisato Tsuboi, Takeshi Ishii, Osamu
Handa, Satoshi Kokura, Hiroshi Ichikawa, Norimasa Yoshida, and Toshikazu
Yoshikawa
Hemin protects dextran sodium sulfate-induced colitis in mice via
induction of heme oxygenase-1.
Third Joint Meeting of the Society for Free Radical Research Australasia
and Japan 2005 (Queensland, Australia), Dec 2005.
Yuji Naito, Wataru Aoi, Satomi Akagiri,
Takeshi Ishii, Yoshikazu Takanami, Yukari Kawai, and Toshikazu Yoshikawa Oxidative stress in delayed-onset muscle
damage after exercise. Third Joint Meeting of the Society for Free Radical
Research Australasia and Japan 2005 (Queensland, Australia), Dec 2005.
Takeshi Ishii, Mitsugu Akagawa, Osamu
Handa, Yuji Naito, and Toshikazu Yoshikawa Mass spectroscopic
characterization of interaction of pyrroloquinoline quinone (PQQ) with
protein. International Interdisciplinary Conference on Vitamins, Coenzymes,
and Biofactors 2005 (Awaji, Hyogo, Japan), Nov. 2005.
Takeshi Ishii, Toyo Sakurai, Shigenori
Kumazawa, Toshihiko Osawa and Koji Uchida
Redox proteomics: identification of
oxidatively modified proteins induced by an endogenous
electrophile.
第77回日本生化学大会 (横浜)、2004年10月
Toyo Sakurai, Takeshi Ishii, Toshihiko
Osawa, and Koji Uchida Molecular target proteins of endogenous aldehydes:
4-hydroxy-2-nonenal, the end product of lipid peroxidation. 第77回日本生化学大会
(横浜)、2004年10月
Mandai Yamada, Takahiro Shibata, Takeshi
Ishii, Toshihiko Osawa, and Koji Uchida Effect of growth factor against
15-deoxy-Δ12,14-prostaglandin J2-induced oxidative
stress and neuronal cell death. 第77回日本生化学大会 (横浜)、2004年10月
Takeshi Ishii, Toyo Sakurai, Shigenori
Kumazawa, Tsutomu Nakayama, Toshihiko Osawa, and Koji Uchida Proteomic
identification of S-thiolated cellular proteins in oxidative stress:
Regulation of alpha-enolase activity by
S-thiolation.
SFRBM’s 10th Annual Meeting (Seattle, USA), Nov.
2003.
Takahiro Shibata, Takaaki Yamada, Takeshi
Ishii, Shigenori Kumazawa, Hajime Nakamura, Hiroshi Masutani, Junji Yodoi, and Koji Uchida Thioredoxin as a molecular target of
cyclopentenone prostaglandins. SFRBM’s 10th Annual Meeting (Seattle, USA),
Nov. 2003.
Takeshi Ishii, Shigenori Kumazawa,
Tsutomu Nakayama, Toshihiko Osawa, and Koji Uchida Oxidative stress
proteomics: identification of S-thiolated cellular proteins during
oxidative stress. 第76回日本生化学会大会 (横浜)、2003年10月
ミニシンポジウム
Miki Ishikawa, Yoshimasa Nakamura, Takeshi
Ishii, Toshihiko Osawa, and Koji Uchida Protein modification by
catechol-type antioxidants. 第76回日本生化学会大会 (横浜)、2003年10月
Takahiro Shibata, Takaaki Yamada, Takeshi
Ishii, Shigenori Kumazawa, Hajime Nakamura, Hiroshi Masutani, Junji Yodoi, and Koji Uchida Thioredoxin as a molecular target of
cyclopentenone prostaglandins. 第76回日本生化学会大会 (横浜)、2003年10月
Takeshi Ishii, Shigenori Kumazawa,
Michiko Okura, Tsutomu Nakayama, Yasuko Fukuda, and Koji Uchida LC/MS
analysis of protein modification by lipid peroxidation products.
4th
International Workshop on advanced Genomics: From Genomics to Proteomics (Kyoto,
Japan), Nov. 2001.
Takeshi Ishii, Shigenori Kumazawa,
Michiko Okura, Tsutomu Nakayama, Yasuko Fukuda, and Koji Uchida Proteomic
studies on oxidatively modified proteins: LC/MS analysis of
malondialdehyde-protein adducts. 5th International Symposium on Mass
Spectrometry in the Health and Life Sciences: Molecular and Cellular Proteomics
(San Francisco, USA), Aug. 2001. Student Award受賞/静岡県立大学はばたき賞受賞
Shigenori Kumazawa, Takeshi Ishii,
Tsutomu Nakayama, Koji Uchida, Miho Koike, and Yasuko Fukuda Antioxidative
activities and inhibitory effects of roasted seed oil on generation of toxic
aldehyde acrolein from heated oil. 11th World Congress of Food
Science and Technology (Seoul, Korea), Apr, 2001.
Yasuko Fukuda, Miho Koike, Shigenori Kumazawa,
Takeshi Ishii, and Koji Uchida Inhibitory effects of roasted seed oil
on generation of toxic aldehyde acrolein from heated oil. Japan Oil
Chemists', American Oil Chemists' Society World Congress 2000 (Kyoto, Japan),
Oct. 2000.