Ito, K., Koike, M., Kuroda, Y., Yamazaki-Ito, T., Terada, Y., Ishii, T., Nakamura, Y., watanabe, T., and Kawarasaki, Y.:Bitternes-masking peptides for epigallocatechin gallate identified through peptide array analysis.,
Food Science and Technology Reseach, In press.
Iwai, R., Ishii, T., Fukushima, Y., Okamoto, T., Ichihashi, M., Sasaki, Y., and Mizutani, K.:Matcha and its components control angiogenic potential.,
Journal of Nutritional Science and Vitaminology, In press.
2018年
Nakagawa Y., Ishimura K., Oya S., Kamino M., Fujii Y., Nanba F., Toda T., Ishii, T., Adachi T, Suhara Y, Osakabe N.:Comparison of the sympathetic stimulatory abilities of B-type procyanidins based on induction of uncoupling protein-1 in brown adipose tissue (BAT) and increased plasma catecholamine (CA) in mice.,
PLoS One. 2018 Jul 30;13(7):e0201203. doi: 10.1371/journal.pone.0201203. eCollection 2018.「査読付き」
Saito, A., Nakazato, R., Suhara, Y., Shibata, M., Fukui, T., Ishii, T., Asanuma,T., Mochizuki, K., Nakayama, T., and Osakabe, N.: The impact of theaflavins on systemic-and microcirculation alterations: The murine and randomized feasibility trials,
Journal of Nutritional Biochemistry
, 32, 107-114 , 2016.「査読付き」
Kudo, N., Arai, Y., Suhara, Y., Ishii, T., Nakayama, T., and Osakabe, N.: A single
oral administration of theaflavins increases energy expenditure and the
expression of metabolic genes,
PLoS One
, 10 (9), e0137809 , 2015.「査読付き」
2014年
Yamazaki, T., Sagisaka, M., Ikeda, R., Nakamura, T., Matsuda,N., Ishii, T., Nakayama, T., and Watanabe, T.:
The human bitter taste receptor hTAS2R39 is the primary receptor for the bitterness of theaflavins,
Bioscience, Biotechnology, and Biochemistry, 78(10), 1753-1756 , 2014.「査読付き」
Aruga, N., Toriigahara, M., Shibata, M., Ishii, T., Nakayama, T., Osakabe, N.:
Responses to a single dose of different polyphenols on the microcirculation and systemic circulation in rats,
Journal of Functional Foods, 10, 355-363 , 2014.「査読付き」
Maeda, A., Kai, K., Ishii, M., Ishii, T., and Akagawa, M.:
Safranal, a novel protein tyrosine phosphatase 1B inhibitor, activates insulin signaling in C2C12 myotubes and improves glucose tolerance in diabetic KK-
Ay mice,
Molecular Nutrition and Food Research, 58, 1177-1189 , 2014.「査読付き」
2013年
Ohnishi, K., Ohkura, S., Nakahata, E., Ishisaka, A., Kawai, Y., Terao, J., Mori, T., Ishii,T., Nakayama, T., Kioka, N., Matsumoto, S., Ikeda, Y., Akiyama, M., Irie, K., and Murakami, A.:
Non-specific protein modifications by a phytochemical induce heat shock response for self-defense,
PLoS One, 8, e58641 , 2013.「査読付き」
2012年
Takada, M., Sumi, M., Maeda, A., Watanabe, F., Kamiya,T., Ishii, T., Nakano, M., and Akagawa, M.:
Pyrroloquinoline quinone, a novel protein tyrosine phosphatase 1B inhibitor, activates insulin signaling in C2C12 myotubes and improves impaired glucose tolerance in diabetic KK-
Ay mice.Biochemical and Biophysical Research Communications, 428 (2) 315-320, 2012.「査読付き」
Kimura, K., Takada, M., Ishii, T., Tsuji-Naito, K., and Akagawa, M.:
Pyrroloquinoline quinone stimulates epithelial cell proliferation by activating epidermal growth factor receptor through redox cycling.
Free Radical Biology and Medicine, 53 (6) 1239-1251, 2012.「査読付き」
Yasuhiro Shinkai, Noriko Iwamoto, Takashi Miura, Takeshi Ishii, Arthur K. Cho, and Yoshito Kumagai:
Redox cycling of 1,2-naphthoquinone by thioredoxin1 through Cys32 and Cys35 causes inhibition of its catalytic activity and activation of ASK1/p38 signaling.
Chemical Research in Toxicology, 25 (6) 1222-30, 2012.
「査読付き」
2011年
Yoshinori Uekusa, Miya Kamihira-Ishijima, Osamu Sugimoto, Takeshi Ishii, Shigenori Kumazawa, Kozo Nakamura, Ken-ichi Tanji, Akira Naito, and Tsutomu Nakayama:
Interaction of epicatechin gallate with phospholipid membranes as revealed by solid-state NMR spectroscopy.
Biochimica et Biophysica
Acta Biomembranes, 1808 (6) 1654-1660, 2011.「査読付き」
Tomoko Tanaka, Takeshi Ishii, Daisuke Mizuno, Taiki Mori, Ryoichi Yamaji, Yoshimasa Nakamura, Shigenori Kumazawa, Tsutomu Nakayama, and Mitsugu Akagawa:
(-)-Epigallocatechin-3-gallate induces growth inhibition of human gastric cancer cell line AZ521 cells by targeting the DEAD box RNA helicase p68.
Free Radical Biology and Medicine, 50 (10) 1324-1335.「査読付き」
Takeshi Ishii, Tatsuya Ichikawa, Kanako Minoda, Koji Kusaka, Sohei Ito, Yukiko Suzuki, Mitsugu Akagwa, Kazuki Mochizuki, Toshinao Goda, and Tsutomu Nakayama:
Human serum albumin as an antioxidant in the oxidation of (-)-epigallocatechin gallate: Participation of reversible covalent binding for interaction and stabilization.
Bioscience, Biotechnology, and Biochemistry, 75 (1) 100-106, 2011.
「査読付き」 (BBB Most-Cited Paper Award 2013)
Kanako Minoda, Tatsuya Ichikawa, Tomoharu Katsumata, Ken-ichi Onobori, Taiki Mori, Yukiko Suzuki, Takeshi Ishii, and Tsutomu Nakayama:
Influence of the galloyl moiety in tea catechins on binding affinity for human serum albumin.
Journal of Nutritional Science and Vitaminology, 56 (5) 331-334, 2010.「査読付き」
Takeshi Ishii, Taiki Mori, Tatsuya Ichikawa, Maiko Kaku, Koji Kusaka, Yoshinori Uekusa, Mitsugu Akagawa, Yoshiyuki Aihara, Takumi Furuta, Toshiyuki Wakimoto, Toshiyuki Kan, and Tsutomu Nakayama:
Structural characteristics of green tea catechins for formation of protein carbonyl in human serum albumin.
Bioorganic and Medicinal Chemistry, 18 (14) 4892-4896, 2010.「査読付き」
Takeshi Ishii, Kanako Minoda, Min-Jung Bae, Taiki Mori, Yoshinori Uekusa, Tatsuya Ichikawa, Yoshiyuki Aihara, Takumi Furuta, Toshiyuki Wakimoto, Toshiyuki Kan, and Tsutomu Nakayama:
Binding affinity of tea catechins for HSA: Characterization by high-performance affinity chromatography with immobilized albumin column.
Molecular Nutrition and Food Research, 54 (6) 816-822, 2010.「査読付き」
Ayako Kato, Hirotaka Naitou, Makoto Namioka, Masanobu Akimoto, Takeshi Ishii, Hiroyuki Sakakibara, Kayoko Shimoi, Tsutomu Nakayama, and Norio Ohashi:
Proteomic identification of serum proteins associated with stress-induced gastric ulcers in fasted rats.
Bioscience,
Biotechnology, and Biochemistry, 74 (4) 812-818, 2010.「査読付き」(BBB論文賞受賞)
Takeshi Ishii, Miyuki Wakabayashi, Taiki Mori, and Tsutomu Nakayama:
A new method for the detection and characterization of α-lipoic acid mixed disulphides.
Free Radical Research, 44 (4)
403-409, 2010. 「査読付き」
Takeshi Ishii, Mitsugu Akagawa, Yuji Naito, Osamu Handa, Tomohisa Takagi, Taiki Mori, Shigenori Kumazawa, Toshikazu Yoshikawa, and Tsutomu Nakayama: Pro-oxidant action of pyrroloquinoline quinone:
characterization of protein oxidative modifications.
Bioscience,
Biotechnology, and Biochemistry, 74 (3) 663-666, 2010.「査読付き」
Yuko Inamochi, Kazuki Mochizuki, Ayumi Osaki, Takeshi Ishii, Tsutomu Nakayama, and Toshinao Goda:
Histone H3 methylation at lysine 4 on the SLC2A5 gene in intestinal Caco-2 cells is involved in SLC2A5 expression.
Biochemical and Biophysical Research Communications, 392 (1) 16-21, 2010.「査読付き」
2009年
Takeshi Ishii, Miki Ishikawa, Noriyuki Miyoshi, Maiko Yasunaga, Mitsugu Akagawa, Koji Uchida, and Yoshimasa Nakamura:
Catechol-type polyphenol is a potential modifier of protein sulfhydryls: development and application of a new probe for understanding the dietary polyphenol actions.
Chemical Research in
Toxicology, 22 (10) 1689-1698, 2009.「査読付き」
Tomohisa Takagi, Yuji Naito, Hitomi Okada, Takeshi Ishii, Katsura Mizushima, Satomi Akagiri, Satoko Adachi, Osamu Handa, Satoshi Kokura, Hiroshi Ichikawa, Ken Itoh, Masayuki Yamamoto, Hirohumi Matsui, and Toshikazu Yoshikawa:
Lansoprazole, a proton pump inhibitor, mediates anti-inflammatory effect in gastric mucosal cells through the induction of heme oxygenase-1 via activation of NF-E2-related factor 2 and
oxidation of kelch-like ECH-associating protein 1.
Journal of Pharmacology and Experimental Therapeutics, 331 (1), 255-264, 2009.「査読付き」
Min-Jung Bae, Takeshi Ishii, Kanako Minoda, Yukiko Kawada, Tatsuya Ichikawa, Taiki Mori, Miya Kamihira, and Tsutomu Nakayama:
Albumin stabilizes (-)-epigallocatechin gallate in human serum: binding capacity and antioxidant property.
Molecular Nutrition and Food Research, 53 (6), 709-715, 2009.「査読付き」 (Food STYLE21 11月号・文献トピックスに紹介)
2008年
Yoshinori Uekusa, Yuko Takeshita, Takeshi Ishii, and Tsutomu Nakayama: Partition coefficients of polyphenols for phosphatidylcholine investigated by HPLC with an immobilized artificial membrane
column.
Bioscience, Biotechnology, and Biochemistry,72 (12) 3289-3292, 2008.「査読付き」
Taiki Mori, Takeshi Ishii, Tomoko Tanaka, Daisuke Mizuno, Ryoichi Yamaji, Shigenori Kumazawa, Tsutomu Nakayama, and Mitsugu Akagawa:
Covalent modification of proteins by green tea polyphenol (-)-epigallocatechin-3-gallate through autoxidation.
Free Radical Biology and Medicine, 45 (10) 1384-1394, 2008.「査読付き」
Takeshi Ishii, Taiki Mori, Shigenori Kumazawa, Tsutomu Nakayama, and Mitsugu Akagawa:
Protein oxidative modification with pyrroloquinoline quinone. Journal of Clinical Biochemistry and Nutrition, 43 (1) 571-574, 2008.
「査読付き」
Taiki Mori, Miyuki Wakabayashi, Takeshi Ishii, Mitsugu Akagawa, and Tsutomu Nakayama:
Mass spectrometry-based study of protein redox modification by alpha-lipoic acid. Journal of Clinical Biochemistry and Nutrition, 43 (1) 456-459, 2008.
「査読付き」
Kousuke Ishino, Takahiro Shibata, Takeshi Ishii, Yu-Ting Liu, Shinya Toyokuni, Xiaochun Zhu, Lawrence M. Sayre, and Koji Uchida:
Protein N-acylation: H2O2-mediated covalent modification of protein by lipid peroxidation-derived saturated aldehydes.
Chemical Research in Toxicology, 21 (6), 1261-1270, 2008.「査読付き」
Kenjirou Ogawa, Hiroyuki Sakakibara, Rei Iwata, Takeshi Ishii, Tsutomu Sato, Toshinao Goda, Kayoko Shimoi, and Shigenori Kumazawa:
Anthocyanin composition and antioxidant activity of the Crowberry (Empetrum nigrum) and other berries.
Journal of Agricultural and Food Chemistry, 56 (12), 4457-4462, 2008.「査読付き」
Takeshi Ishii, Sohei Ito, Shigenori Kumazawa, Toyo Sakurai, Satoru Yamaguchi, Taiki Mori, Tsutomu Nakayama, and Koji Uchida:
Site-specific modification of positively-charged surfaces on human serum albumin by malondialdehyde.
Biochemical and Biophysical Research Communications, 371 (1), 28-32, 2008.
「査読付き」
Wataru Aoi, Yuji Naito, Yoshikazu Takami, Takeshi Ishii, Yukari Kawai, Satomi Akagiri, Yoji Kato, Toshihiko Osawa, and Toshikazu Yoshikawa:
Astaxanthin improves muscle lipid metabolism in exercise via inhibitory effect of oxidative CPT I modification.
Biochemical and Biophysical
Research Communications, 366 (4), 892-897, 2008.「査読付き」
2007年
Takeshi Ishii, Tomoe Yamada, Taiki Mori, Shigenori Kumazawa, Koji Uchida, and Tsutomu Nakayama:
Characterizatrion of acrolein induced protein cross-links.
Free Radical Research, 41 (11), 1253-1260, 2007.
「査読付き」
Noriko Iwamoto, Daigo Sumi, Takeshi Ishii, Koji Uchida, Arthur K. Cho, John R. Froines, and Yoshito Kumagai:
Chemical knockdown of protein tyrosine phosphatase 1B by 1, 2-naphthoquinone through covalent modification cause persistent transactivation of epidermal growth factor receptor.
Journal of Biological
Chemistry, 282 (46), 33396-33404, 2007.「査読付き」
Mitsugu Akagawa, Yoshihisa Ishii, Takeshi Ishii, Takahiro Shibata, Mari Yotsu-Yamashita, Kyozo Suyama, and Koji Uchida:
Metal-catalyzed oxidation of protein-bound dopamine.
Biochemistry,
45 (50), 15120-15128, 2006.「査読付き」
Takeshi Ishii, Shigenori Kumazawa, Toyo Sakurai, Tsutomu Nakayama, and Koji Uchida:
Mass spectroscopic characterization of protein modification by malondialdehyde.
Chemical
Research in Toxicology, 19 (1), 122-129, 2006.
「査読付き」(The 10 most accessed articles of 2006 from Chemical Research in Toxicology)
2005年
Takeshi Ishii, Sakurai, T., Usami, H., and Uchida, K.: Oxidative modification of proteasome:identification
of an oxidation- sensitive subunit in 26S proteasome Biochemistry, 44, 13893-13901, 2005.
「査読付き」(2005 ACS Hot Articles)
Takeshi Ishii, and Uchida, K.: Induction of reversible cysteine-targeted protein oxidation
by an endogenous electrophile 15-deoxy-delta12,14-prostaglandin J2, Chemical Research in Toxicology, 17, 1313-1322, 2004.
「査読付き」
2003年
Atsunori Furuhata, Takeshi Ishii, Shigenori Kumazawa, Tomoe Yamada, Tsutomu Nakayama, and Koji Uchida:
N-(3-Methylpyridinium)lysine, a major antigenic adduct generated in acrolein-modified protein.
Journal of Biological Chemistry, 278 (49), 48658-48665, 2003.
「査読付き」
Takahiro Shibata, Takaaki Yamada, Takeshi Ishii, Shigenori Kumazawa, Hajime Nakamura, Hiroshi Masutani, Junji Yodoi, and Koji Uchida:
Thioredoxin as a molecular target of cyclopentenone prostaglandins.
Journal of Biological Chemistry, 278 (28), 26046-26054, 2003.
「査読付き」
Takeshi Ishii, Emi Tatsuda, Shigenori Kumazawa, Tsutomu Nakayama, and Koji Uchida: Molecular basis of enzyme inactivation by an endogenous electrophile 4-hydroxy-2-nonenal:
Identification of modification sites in glyseraldehyde-3-phosphate dehydrogenase.
Biochemistry, 42 (12), 3474-3480, 2003.
「査読付き」
Koike, M., Ito, K., Kuroda, Y., Ishii, T., Nakamura, Y., Watanabe, T., and Kawarasaki, Y.:
EGCG-binding peptides from green tea leaves as bitterness-masking agents、
The 20th Shizuoka Forum on Health and Longevity
(Shizuoka, Japan)、
2015年
10月
30日
ポスター賞受賞
Tsutomu Nakayama., Kanako Matsuura., and Takeshi Ishii.:
A novel method to evaluate antioxidant activity of polyphenols、
2015 KFN International Symposium and Annual Meeting
(Peongchang, Korea)、
2015年
8月
24‐26日
Nakamura T, Yamazaki T, Sagisaka M, Ikeda R, Matsuda N., Ishii T., Nakayama T., Watanabe T.:
TAS2R39 Theaflavins activate human taste receptor. The 2nd International Conference on Pharma and Food, (Shizuoka) , 2014年11月6日「ポスター発表」
Mori, T., Katsumata, T., Akagawa, M., Nakayama, T., and Ishii, T.:
Development and application of a new probe for searches for the high-affinity proteins of gallate-type catechins, 27th International Conference on Polyphenols (Nagoya), 2014年9月5日「ポスター発表」
Nakayama, T., Matsuura, K., Usui, Y., Kan, T., and Ishii, T.:
Structural specificity of electric potentials in the coulometric-array analysis of catechins, methylated catechins and theaflavins, 27th International Conference on Polyphenols (Nagoya), 2014年9月5日「ポスター発表」
前田歩海、甲斐建次、石井 恵、石井剛志、赤川 貢、芦田 均:
サフラナールによる protein tyrosine phosphatase 1B(PTP1B)の阻害を介したインスリンシグナリング活性化作用の解明、日本食品科学工学会第61回大会(福岡)、 2014年8月30日「口頭発表」
Matsuura, K., Usui, Y., Ishii, T., and Nakayama T.:
Structural specificity of electric potential in coulometric-array analysis of tea polyphenols, The 5th International Conference on O-CHA (Tea) Culture and Science (Shizuoka, Japan), 2013年11月8日「ポスター発表」
Hayashi, M., Yasui, M., Saito, N., Nakayama, T., Ishii, T.:
A new method involving detection of protein aggregation for evaluating the astringency of tea polyphenols, The 5th International Conference on O-CHA (Tea) Culture and Science (Shizuoka, Japan), 2013年11月8日「ポスター発表」
Yamazaki, T., Sagisaka, M., Matsuda, N., Ishii, T., Nakayama, T., and Watanabe, T.:
TAS2R39 is a bitter taste receptor for theaflavins, The 5th International Conference on O-CHA (Tea) Culture and Science (Shizuoka, Japan), 2013年11月8日「ポスター発表」
Takahashi, Y., Nakagawa, A., Ohtaki, T., Takeda, A., Takeuhi, Y., Ishii, T., Nakayama, T., Konishi, T., and Unno, K.:
Effect of green tea catechin for prevent of age-related brain dysfunction, The 5th International Conference on O-CHA (Tea) Culture and Science (Shizuoka, Japan), 2013年11月8日「ポスター発表」
Watase, T., Ikegaya, A., Yugami, T., Hakamata, M., Takagi, H., Kamimura, M., Dohi, S., Tanzawa, N., Shiotani, S., Takahashi, C., Suzuki, T., Nakayama, T., and Ishii, T.:
Application of bitterness and/or astringency control material to tea products, The 5th International Conference on O-CHA (Tea) Culture and Science (Shizuoka, Japan), 2013年11月7日「ポスター発表」
Shiotani, S., Takahashi, C., Ogawa, M., Shibuya, E., Mitarai, H., Yasui, M., Saito, N., Ito, S., Suzuki, T., Yanai, N., Nakayama, T., and Ishii, T.:
Development of a new soybean-protein derived taste-masking agent that lowers bitterness and/or astringency of tea polyphenols, The 5th International Conference on O-CHA (Tea) Culture and Science (Shizuoka, Japan), 2013年11月7日「ポスター発表」
Ohta, Y., Asanuma, T., Suzuki, T., Nakayama, T., and Ishii, T.:
Polyphenol-caffeine complexes mediate tea creaming in black tea, The 5th International Conference on O-CHA (Tea) Culture and Science (Shizuoka, Japan), 2013年11月7日「ポスター発表」